Borderlands 4 brings major improvements to gameplay, gunplay and character progression, while finally delivering a true open-world experience. Hardware requirements are steep, though. In our performance review, we examine its graphical fidelity, VRAM usage, and how well it runs on a variety of modern GPUs.
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My poor RX 6600 that is driving a 2560x1440p monitor has no chance [1].

References
  1. Type: Meta
    • At 2560x1440, the RX 7600XT performs at 17.9FPS in Borderlands 4 [2]. Given that the RX 7600XT is, in general, more performant than the RX 6600 [3], it is presumed that the RX 6600 will perform very poorly at 2560x1440 in Borderlands 4.
  2. Type: Article. Title: “Borderlands 4 Performance Benchmark Review - 30+ GPUs Tested”. Author: “W1zzard”. Published: 2025-09-12T12:44:00+00:00. Accessed: 2025-09-15T01:42Z. Publisher: “www.techpowerup.com” (“TECHPOWERUP”). URI: https://www.techpowerup.com/review/borderlands-4-performance-benchmark/5.html.
  3. Type: Webpage. Publisher: “UserBenchmark”. Accessed: 2025-09-15T01:44Z. URI: https://gpu.userbenchmark.com/Compare/AMD-RX-7600-XT-vs-AMD-RX-6600/m2280266vs4128.

    • The RX 7600-XT has an average score of 49.6%, surpassing the RX 6600’s average score of 36.4% (higher is better).
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